Things turn deadly when elite matchmaker Margo Clarke goes to extreme lengths to keep her socialite client from finding out the truth about her perfect new husband.
The BAU is called to investigate after the bodies of missing people are discovered in a remote region of the Idaho wilderness.
When two New York City paramedics are killed during a kidnapping, Holmes and Watson join the manhunt to find the murderer and the woman he abducted. Also, Holmes learns important information about his recovery sponsor, Alfredo (Ato Essandoh), that strains their relationship.
Danny contemplates retiring until Erin enlists him to help her with a case involving her ex-husband, Jack (Peter Hermann). Also, Jamie and Eddie go undercover as a couple, and Frank butts heads with the new mayor of New York City, Margaret Dutton (Lorraine Bracco).
Danny and Baez are temporarily assigned new partners when an officer is outed and his current partner won't ride with him. Meanwhile, Jamie and Eddie work on a revenge mission to steal a collar from a pompous detective, and Frank compromises his relationship with the Archdiocese when he speaks out about equality in the police force.