Things turn deadly when elite matchmaker Margo Clarke goes to extreme lengths to keep her socialite client from finding out the truth about her perfect new husband.
The BAU is called to investigate after the bodies of missing people are discovered in a remote region of the Idaho wilderness.
When two New York City paramedics are killed during a kidnapping, Holmes and Watson join the manhunt to find the murderer and the woman he abducted. Also, Holmes learns important information about his recovery sponsor, Alfredo (Ato Essandoh), that strains their relationship.
Lincoln Burrows is scheduled to die on death row for an assassination his younger brother Michael is convinced he did not commit. With no other options and time running out, Michael takes drastic measures to get incarcerated alongside his brother. Once inside, Michael – a structural engineer with the blueprints for the prison – begins to execute an elaborate plan to break Lincoln out and prove his innocence.
Danny contemplates retiring until Erin enlists him to help her with a case involving her ex-husband, Jack (Peter Hermann). Also, Jamie and Eddie go undercover as a couple, and Frank butts heads with the new mayor of New York City, Margaret Dutton (Lorraine Bracco).