A series of flashbacks to three years ago unveils how Lincoln, Sucre, T-Bag, C-Note and Dr. Sara landed in Fox River State Penitentiary, and what drove Michael to craft his elaborate plan to break his condemned sibling out of the prison.
With Lincoln’s execution scheduled for the following day, Veronica reaches out to him and gains a newsworthy ally in the process. Meanwhile, Michael must find a way to get Lincoln out of solitary confinement and the inmates risk everything as they attempt the escape of their lives.
As Michael struggles to remember missing pieces of the prison schematics, Warden Pope places him in solitary when he refuses to name names. Meanwhile, Sucre is left to pave over the escape hole in the guards’ room before a carpeting team can find it.
Michael and Lincoln experience car trouble as Mahone’s pursuit of them goes up in flames; Sucre hits the road to stop Maricruz from taking a gamble; C-Note is determined to reunite with his wife and daughter despite their surveillance; a familiar face keeps a close eye on Sara, who finds the tables turned on her; determined to cash in on the prison break, Bellick partners with an unlikely ally.
Michael puts the moves on Mahone's wife in hopes of digging up dirt on his pursuer. Lincoln and LJ have an uneasy road trip; C-Note's wife must choose between her husband and her daughter; and T-Bag gets an unwelcome surprise while looking for a lost love.
