Izzie returns to work while the Seattle Grace residents fear possible layoffs; Bailey and Alex's difficult case is further complicated by her schizophrenic son.
When a serial kidnapper “over there” strikes again, the familiar case hits home for Colonel Broyles, who sends a determined Olivia to investigate the abductions.
Walter travels to the Alternate Universe to assist in the investigation of a Fringe event with ties to both worlds. Meanwhile, David Robert Jones reveals his next target.
Mark, Demetri and Wedeck try to find a connection between Janis' attack and a separate attack made on them; Demetri and Gough track down a clue that was foreshadowed in Mark's flashforward; Simon makes contact with a reluctant acquaintance.
The "Boys of Nick" compete in a series of mental and physical challenges centered on the internet's best viral videos. Featuring Curtis Harris, Cameron Ocasio, Tylen Williams, Jack Griffo
