Captain Tom Chandler and the crew of the USS Nathan James set out for the Arctic with two civilian virologists who claim to be studying birds.
The death of a Navy officer leads Gibbs and the team into the world of high-priced call girls, relying on D.C. Madam Holly Snow to help them catch a killer.
Chandler and his crew head to the U.S. Military base at Guantanamo Bay in hopes of collecting food, medical supplies and fuel replenishments.
Days after a trying series of events at Gitmo, Chandler and his crew are put under extreme duress when the ship's propulsion system suffers a catastrophic event. With Dr. Scott in danger of losing all her research on the virus and a crew overworked, overtired and desperately low on drinking water, Chandler's leadership and ingenuity are put to the test.
With Rachel close to a breakthrough on her vaccine, she, Chandler and XO Slattery lead a small team into the jungles of Nicaragua on a mission to find monkeys for her vaccine trials.