Murders involving overweight women lead Mulder and Scully to the trail of a mutant killer who may be feeding on the fat of his victims.
After a serial killer is executed in Texas, his daughter brings him home for a fitting Fisher & Diaz funeral. Meanwhile, Ruth spends some quality time in the company of George Sibley; David arrives at a crossroads in his relationship with Keith; Rico can't find refuge from his domestic demons; and Nate and Claire get lost in their own separate twilights.
Tommy and Ernie encounter Jill, Tommy's ex-girlfriend.
Ellen deals with the ramifications of telling her parents she's gay.
After reading a self-help book, Vera (Beth Howland) feels ready to prove she's responsible. But when Mel (Vic Tayback) leaves her in charge of the diner for a few minutes, all hell breaks loose.