House recounts the case of a woman who came to the emergency room with an unexplained illness and no memory of her identity.
Phil, Will and Carlton are taken hostage by a crazed, bomb-toting clown.
The Wellness Center starts a "Dads-to-be" class, much to Charlotte's displeasure; Sam and Naomi struggle to figure out where their relationship is going; Addison is conflicted about her status in the dating world; Cooper begins a secret affair with one of his colleagues.
An abandoned horse covered in blood leads the CSI team to a halfway house for convicted murderers. Also, Grissom and Sara begin to circle their prime suspect in the David Hodges case.
Agent Jack Bauer's intense interrogation uncovers both new leads and incriminating evidence, but his tactics have devastating consequences. Meanwhile, problematic President Logan faces more troubling issues.