Vince is blinded by love, and Eric gets cozy with Sloan. Meanwhile, Ari gets shot down in the war room, and Drama and Turtle use their paparazzi skills on an important spy mission.
When Dr. Alicia Seberg, a government research scientist (guest star Amy Price-Francis), is exposed to a deadly toxin while at work and has only hours to live, she calls Patrick Jane and the CBI to find her murderer.
Warrick looks into the murder of man by someone who apparently needs a wheelchair. Nick looks into the murder of woman in the subculture of the narcocorrido, songs about drug murders.
Team Scorpion gets trapped inside a failing and dangerous biodome designed for Mars while trying to extract a pair of scientists inside.
When Sharona returns to San Francisco to handle legal issues related to an uncle's death, Monk suspects foul play and finds himself torn between the differing styles of Sharona and Natalie. Bitty Schram guest stars.