MacGyver grieves for his long-time friend, who dies in a tragic rock climbing accident. However, the return of an old enemy forces him back into action.
MacGyver faces a busy Christmas Eve: he tries to help a priest reclaim a stolen Madonna figure, aids Cynthia in keeping the Challenger Club's doors open, and comes to the rescue of a bag lady preyed upon by thieves.
After getting caught in a wolf trap, MacGyver finds himself being cared for by two determined ladies running an isolated bed and breakfast which a mob accountant is using to hide out with his stolen million dollars.
Vinnie's assignment to check out a contract killer leads him into a huge global contraband syndicate-- an operation that far exceeds the scope of the Steelgrave family-- overlorded by brother and sister Mel and Susan Profitt.