Angela Relucio

Howard receives some shocking news as everyone prepares for the reopening of Stuart's comic book store. Penny teaches Sheldon how to “let it go” but can't follow her own advice after she learns something infuriating about Amy. Also, Leonard and Raj think they spot Nathan Fillion at a restaurant.

After Christa saves a woman's life, she pleads with Neal to perform a surgery that will ensure the patient's reproductive future. Also, Mario gets into a fight with a patient after he delivers a diagnosis that could imperil the man’s hockey career.

Amid the chaos and exhaustion of working 36 consecutive hours in Code Black, the doctors must deal with Margaret O'Brien (Gail O'Grady), the distraught mother of two sons who are in a devastating car accident. Also, Mario bullies Angus into performing an unnecessary operation but lets Angus take the blame when Leanne finds out.

Christa has her busiest shift yet when she is responsible for all emergencies at Angels Memorial that occur outside of the E.R. Also, Mario bonds with an older patient with HIV, Malaya starts a bone marrow drive for Carla (Shiri Appleby) and Leanne refuses a date with Cole (Cress Williams).

A new surgical attending Cole Guthrie (Cress Williams) joins Angels Memorial with the help of his estranged father and clashes with Leanne over their contrasting approaches to medicine. Also, Christa has a crisis of confidence in the middle of a procedure on her first infant since the loss of her son.