After an ex-convict makes a daring escape from the BAU's custody and embarks on a killing spree in Lockport, New York, the team must profile the criminal's past in order to catch him again.
Danny and Maria investigate when a homeowner shoots an intruder, only to find out that the intruder is a hitman. Also, a young attorney attempts to bring justice to his mother who Erin put away on a murder charge 12 years ago.
Lightman goes head-to-head with the leader of a self-help empire (guest star David Sutcliffe) to free a wealthy woman (guest star Julia Campbell) who may be under the control of the cult-like leader. When Lightman begins to investigate, things get personal as he suspects the group of threatening him and his daughter, Emily.
Emotions are stirred up at the practice when Dell's daughter arrives; a pregnant woman experiences chronic pain.
Scanlon is haunted by dreams of his late brother, leaving Allison concerned about her colleague. Also, while making her final preparations for college, Ariel has visions of missing young women, past and present.