When a 200-year-old medicine jar shatters in a teenager's palm, she is admitted to the hospital with symptoms closely linked to smallpox; House must make a dangerous decision that puts his life in jeopardy; Wilson and Sam comfort a young patient.
When teenagers who were reported missing are suspected of a series of mass murders in Chicago, the BAU investigates their whereabouts to find a motive for the crimes.
The murder of an ex-convict triggers an investigation of his social-climbing sister and her beau, a man posing as a United Nations economist.
The CSI team investigates a robbery and fatal shooting at a medical marijuana shop.
While investigating a vicious tiger mauling at a New York zoo, the CSIs question the workers at the meatpacking plant the victim owned. Meanwhile, Stella and Dr. Hawkes must solve the murder of a debutante found dead on a Central Park carousel. Also, a new CSI (Anna Belknap) joins the team. (TV-14)