Amy J. Carle

Two airplane stowaways are brought into the hospital after suffering major injuries from the travel, prompting Sharon Goodwin (S. Epatha Merkerson) to receive a visit from the Department of Homeland Security regarding the undocumented immigrants. Cornelius Rhodes (guest star DW Moffett), the wealthy father of Dr. Connor Rhodes (Colin Donnell), is honored after making a big donation to the hospital for a new psych ward, forcing dark family secrets to the surface. Dr. Natalie Manning's (Torrey De Vitto) big day arrives and Dr. Will Halstead's (Nick Gehlfuss) good intentions to help are misconstrued by her mother-in-law, Helen (guest star Annie Potts). Meanwhile, Dr. Sarah Reese (Rachel DiPillo) asks Dr. Charles (Oliver Platt) for advice on how to deliver heartbreaking news to a young boy while also warning his family about the possibility that their other son may also have the same life-threatening disease.

Dr. Halstead (Nick Gehlfuss) and Sharon Goodwin (S. Epatha Merkerson) deal with a husband intent on harvesting his recently deceased wife's eggs, but soon discover some vital information that surprises everyone. Dr. Charles (Oliver Platt) is brought in by Dr. Choi (Brian Tee) to aid a patient who is trying to remove his own arm from his body because he feels like it doesn't belong. Nurse Sexton (Yaya DaCosta) befriends the father of a child who is rushed into the hospital after swallowing magnets - a situation that Dr. Rhodes (Colin Donnell) and Dr. Manning (Torrey DeVitto) are concerned could present dangerous complications. Meanwhile, Sarah Reese (Rachel DiPillo) finally learns about where she will do her residency, but has last-minute second thoughts.

Dr. Manning (Torrey DeVitto) and Dr. Charles (Oliver Platt) deal with a 16-year-old patient suffering from abdominal pain who adamantly refuses any drugs for fear of winding up like her drug-addicted father. Dr. Halstead (Nick Gehlfuss) relives a bit of his past when a patient, along with his brother, turn out to be former high school classmates whose past history with him is anything but stellar. Meanwhile, Dr. Choi (Brian Tee) works on a woman 32 weeks pregnant who has a big reason to do everything in her power not to deliver the child, much to the dismay of Goodwin (S. Epatha Merkerson), Charles and the hospital staff. Elsewhere, April (Yaya DaCosta) is less than thrilled to discover her brother Noah (guest star Roland Buck III) has an enterprising side-business that involves her new boyfriend Tate (guest star Deron J. Powell). Dr. Rhodes (Colin Donnell) avoids meeting up with his sister Claire (guest star Christina Brucato) so he doesn't have to deal with family issues. Rachel DiPillo and Marlyne Barrett also star.

Lieutenant Severide (Taylor Kinney) returns to Firehouse 51, but he is clearly not his usual self and Dawson (Monica Raymund) counts down the weeks until she gets started as a candidate at the Austin Firehouse. Meanwhile, Mills (Charlie Barnett) learns more about his father’s family and Herrmann (David Eigenberg) asks the rest of the Molly investors to come up with some new ideas to turn the business around.

When a massive helicopter explosion in a densely populated area leaves a trail of debris scattered across a full city block, members of the firehouse spring into action as lives hang in the balance. Squad 3 finds itself in a precarious position, Brett (Kara Killmer) is cornered by a dangerous man in the midst of the madness and Dawson (Monica Raymund) is shocked to discover what actually brought the chopper down.