Susan upsets an important client; Renee and Gabrielle reveal secrets about each other; Emma Graham plans a cabaret show.
Meredith and Derek rediscover the morning-after side of their relationship; the chief learns the hospital has slipped in the national rankings.
Cristina, back from her honeymoon trip, searches in vain for Burke; Meredith, Cristina, Izzie and Alex spend their first day as residents with their own groups of interns
George and Izzie's romantic chemistry is put to the test. Mark develops a crush on a fellow surgeon. Callie's role as chief resident is in jeopardy.
The new interns are dazzled by the skill level of fellow intern George, while Lexie helps keep his "repeater" status a secret; Meredith half-heartedly helps Lexie with her first emergency patient.
