House exasperates Cuddy when he suggests that two sick babies in one hospital add up to an epidemic. Even more frightening is when it turns out he may be right. As more babies are quarantined and the maternity ward is shut down, Cuddy powerscrubs the hospital and House spars with Cameron and the team over his plan to sacrifice one baby for the good of the rest.
The murder of a man connected to smuggling Turkish relics sends Castle, Beckett and the 12th Precinct on a search for a stolen antique believed to be Aladdin's lamp, in hopes that it can lead them to the killer.
Melinda tries to help an angry ghost clear his name when she sees him in a restaurant that is burning down for the second time.
Jimmy is torn between family and work after his father-in-law, Ed (Larry Miller), asks him to tamper with evidence from NCIS' current murder investigation. Also, Ed's poker buddy, Anthony DiNozzo, Sr. (Robert Wagner), offers to help with the case.
George and Jerry are suspected of roughing up Bette Midler in a softball game, giving Jerry's girlfriend, Bette's understudy, a chance to take the stage.