In the season premiere, Damon is forced to navigate his new reality without the love of his life. Stefan takes an active role in protecting the town from Lily (Annie Wersching).
Severide, Kidd and Van Meter investigate a fire at a recording studio. Kylie helps James keep a secret from Boden. Mouch struggles to maintain boundaries with a paramedicine client.
The NCIS team investigates the murder of a petty officer who was in town to help a refugee family being recruited by terrorists. Also, Wade works on the special election campaign for Mayor Zahra Taylor that takes place during Mardi Gras. Amanda Warren guest stars.
Ichabod and Abbie fight against those who want to re-awaken a powerful witch coven and Jenny learns a disturbing truth about Frank Irving.
While familiar faces begin to reappear, Black Lightning is recruited to rally against The 100 gang, and Anissa investigates a new drug hitting the streets.
